http://petrieflom.law.harvard.edu/events/details/digital-health-harvard-series-november-2018 Harvard Law School
Wasserstein Hall, Milstein East (2036) 1585 Massachusetts Ave.
Cambridge, MA 02138
"Infectious disease emergencies are opportunities to test the efficacy of newly developed interventions (eg drugs, vaccines and treatment regimens), yet they raise many intertwined challenges of politics, logistics, ethics, and study design. Consistent with the efforts of CEPI, WHO, and others to encourage development and Phase I/II testing of candidate vaccines (the focus of this talk) in advance of emergencies, it is essential before the emergency strikes to advance the discussion of how such products can and should be tested. This can help to disentangle ethical from political and logistical concerns, reduce the time pressure to make a decision, and encourage rational deliberation by future stakeholders who at the time of deliberation do not know what role (which product, which field site) they may be supporting in an actual emergency.
This luncheon will describe Professor Lipsitch’s work on computer simulation of vaccine trials during epidemics to assess options for trial design, as well as some of his recent work on the ethics of trials in emergencies, with the aim to stimulate discussion on the intersection of these two topics."